t 4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16967	T-00127_HEV1		PI4K
	T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM).		PI4K
T0864	L-Thyroxine	Levothyroxine,NSC 36397,T4	Thyroid hormone receptor(THR) , Endogenous Metabolite
	L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...		Thyroid hormone receptor(THR) , Endogenous Metabolite
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T35719	T2AA	T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533	DNA/RNA Synthesis
	T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth ...		DNA/RNA Synthesis
T3189	B7/CD28 interaction inhibitor 1	CTLA-4 inhibitor	Others
	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.		Others
T22355	L-Thyroxine sodium	LT4 sodium,Levothyroxine sodium,L-T4 sodium	Thyroid hormone receptor(THR)
	L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.		Thyroid hormone receptor(THR)
T6690	T0901317		Apoptosis , FXR , Liver X Receptor , ROR
	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).		Apoptosis , FXR , Liver X Receptor , ROR
T6603	Nelarabine	GW 506U78,Nelzarabine,506U78	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
T1653	Liothyronine	Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T20557	Thyroxine sulfate	T4 Sulfate
	Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.
T69799	4-Me-PDTic
	4-Me-PDTic is a potent and selective kappa opioid receptor antagonist.
T34272	RC 121	RC121,IM 4-28,RC-121,P-Cttlvc-T
	RC 121 is a highly potent somatostatin (SRIF) analog.
T39619	FmocNH-PEG4-t-butyl ester	FmocNH-PEG4-t-butyl ester
	FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasom...
T41024	FmocNH-PEG4-t-butyl acetate	FmocNH-PEG4-t-butyl acetate
	FmocNH-PEG4-t-butyl acetate is a polyethylene glycol (PEG)-derived PROTAC linker employed for the synthesis of PROTACs, bifunctional molecules designed to degrade target proteins.
T39532	Bis-PEG4-t-butyl ester	Bis-PEG4-t-butyl ester
	Bis-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome s...
T18741	t-Boc-Aminooxy-PEG4-NHS ester		Others
	t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative, functioning as a linker for PROTAC synthesis[1].		Others
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
TNU1322	3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine
	Nucleoside Derivatives - 4’-Modified nucleosides
T16238	N-Methyl-N-(t-Boc)-PEG4-acid		Others
	N-Methyl-N-(t-Boc)-PEG4-acid is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker in the synthesis of PROTACs, which refers to proteolysis-targeting chimeras[1].		Others
T16053	Methylamino-PEG4-Boc	Methylamino-PEG4-t-butyl ester	Others
	Methylamino-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...		Others